Concepedia

Transgenic Mouse Models

Transgenic Mouse Model is a genetically engineered animal model in which exogenous DNA has been stably integrated into the mouse genome through transgenesis, enabling the study of gene function, regulation, or disease pathogenesis in a mammalian system.

12.5K

Publications

930.4K

Citations

68K

Authors

6K

Institutions

Publications per year

2017–2026

2.9K

Parents

Publications

12.5K

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

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Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.6K citations · Full text

, , +17

‘Green mice’ as a source of ubiquitous green cells

Masaru Okabe, Masahito Ikawa, Katsuya Kominami et al. · FEBS Letters · 1997 · 2.6K citations

, , +17

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations

, , +17

In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

Noboru Mizushima, Akitsugu Yamamoto, Makoto Matsui et al. · Molecular Biology of the Cell · 2003 · 2.3K citations · Full text

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1–5 of 12.5K

Authors

68K

  1. EM
    Eliezer Masliah

    University of California San Diego, United States

    40 publications · 8.3K citations

    36

    h-index

  2. JQ
    John Q. Trojanowski

    University of Pennsylvania, United States

    31 publications · 5.1K citations

    28

    h-index

  3. MR
    Michael R. Hayden

    University of British Columbia, Canada

    31 publications · 3.9K citations

    28

    h-index

  4. DB
    David Borchelt

    University of Florida, United States

    35 publications · 3.6K citations

    28

    h-index

  5. WJ
    William J. Muller

    McGill University, Canada

    35 publications · 4.3K citations

    28

    h-index

1–5 of 68K

Institutions

6K

  1. Harvard University

    Cambridge, United States

    112 h-index

    1.7K publications

    175.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    106 h-index

    667 publications

    102.6K citations

  3. Inserm

    Paris, France

    88 h-index

    2K publications

    146.1K citations

  4. University of California, San Francisco

    San Francisco, United States

    87 h-index

    840 publications

    114.2K citations

  5. University of Pennsylvania

    Philadelphia, United States

    87 h-index

    912 publications

    100K citations

  6. National Institutes of Health

    Bethesda, United States

    86 h-index

    1.1K publications

    116.1K citations

  7. Baylor College of Medicine

    Houston, United States

    82 h-index

    929 publications

    96.2K citations

  8. Johns Hopkins University

    Baltimore, United States

    81 h-index

    969 publications

    100.1K citations

1–8 of 6K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 480 publications · 83.5K citations

    162

    h-index

  2. Journal of Neuroscience

    305 publications · 55.1K citations

    136

    h-index

  3. Journal of Clinical Investigation

    JCI · 149 publications · 24.9K citations

    87

    h-index

  4. Human Molecular Genetics

    224 publications · 20K citations

    86

    h-index

  5. PubMed

    Repository · 405 publications · 24.1K citations

    81

    h-index

1–5