William J. Muller

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

William J. Muller, Eric Sinn, Paul K. Pattengale et al. · Cell · 1988 · 1.2K citations

Oncogenic Agent, Medicine, Immunology +10

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

Elaine Y. Lin, Joan G. Jones, Ping Li et al. · American Journal Of Pathology · 2003 · 1.1K citations · Full text

Tumor Biology, Reliable Model, Oncology +11

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Krushna C. Patra, Qi Wang, Prashanth T. Bhaskar et al. · Cancer Cell · 2013 · 839 citations · Full text

Tumor Biology, Medicine, Hexokinase 2 +9

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

Eric Sinn, William J. Muller, Paul K. Pattengale et al. · Cell · 1987 · 798 citations

Knockout Mouse, Oncogenic Agent, Immunology +8

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang, Cong S. Zong, Weiya Xia et al. · Nature Cell Biology · 2008 · 693 citations · Full text

Mdm2-mediated Degradation, Medicine, Tumor Suppressor +4