William J. Muller

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

William J. Muller, Eric Sinn, Paul K. Pattengale et al. · Cell · 1988 · 1.2K citations

Medicine, Cancer Biology, Oncology +14

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

Elaine Y. Lin, Joan G. Jones, Ping Li et al. · American Journal Of Pathology · 2003 · 1.1K citations · Full text

Medicine, Cancer Biology, Oncology +14

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Krushna C. Patra, Qi Wang, Prashanth T. Bhaskar et al. · Cancer Cell · 2013 · 859 citations · Full text

Medicine, Cancer Biology, Oncology +17

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo

Eric Sinn, William J. Muller, Paul K. Pattengale et al. · Cell · 1987 · 799 citations

Medicine, Genetics, Molecular Biology +16

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

Jer-Yen Yang, Cong S. Zong, Weiya Xia et al. · Nature Cell Biology · 2008 · 699 citations

Medicine, Cancer Biology, Cell Biology +12