Sarah L. Cole

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.4K citations · Full text

The Alzheimer's disease Beta-secretase enzyme, BACE1

Sarah L. Cole, Robert Vassar · Molecular Neurodegeneration · 2007 · 529 citations · Full text

Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis

Tracy O’Connor, Katherine R. Sadleir, Erika Maus et al. · Neuron · 2008 · 411 citations · Full text

Signal Transduction, Protein Expression, Natural Sciences +8

Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1

Qiang Liu, Celina Zerbinatti, Juan Zhang et al. · Neuron · 2007 · 360 citations · Full text

Brain Apolipoprotein E, Cholesterol Metabolism, Alzheimer's Disease +7

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Masuo Ohno, Sarah L. Cole, Marina V. Yasvoina et al. · Neurobiology of Disease · 2006 · 291 citations · Full text

Memory Deficits, Neurodegenerative Diseases, Neuroregeneration +10