Concepedia

Systems Pharmacodynamics

Systems Pharmacodynamics is a quantitative modeling approach within pharmacodynamics that applies systems biology–based, multiscale and network models to mechanistically characterize and predict the time course of drug effects on complex physiological and pathophysiological systems across levels of biological organization.

22

Publications

870

Citations

75

Authors

38

Institutions

Publications per year

2017–2026

2

Parents

Children

Publications

22

Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development

Piet H. van der Graaf, Neil Benson · Pharmaceutical Research · 2011 · 242 citations

, , +16

Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction

Yao Yao, Xiaodong Zhang, Zhenzhong Wang et al. · Journal of Ethnopharmacology · 2013 · 116 citations

, , +11

Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases

Peng Li, Jianxin Chen, Jinan Wang et al. · Journal of Ethnopharmacology · 2013 · 67 citations

, , +14

Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems

Jun Yang, Donald E. Mager, Robert M. Straubinger · The AAPS Journal · 2009 · 51 citations

, , +16

Relevance of systems pharmacology in drug discovery

L. Cucurull-Sanchez, Karen G. Spink, Sterghios Moschos · Drug Discovery Today · 2012 · 42 citations

, , +13

1–5 of 22

Authors

75

  1. PV
    Peter Veng‐Pedersen

    University of Iowa, United States

    3 publications · 56 citations

    3

    h-index

  2. LY
    Ling Yang

    Dalian Institute of Chemical Physics, China

    3 publications · 203 citations

    3

    h-index

  3. WR
    William R. Gillespie

    University of Iowa, United States

    2 publications · 42 citations

    2

    h-index

  4. HS
    Hans Schaefer

    Galderma (France), France

    2 publications · 31 citations

    2

    h-index

  5. YW
    Yonghua Wang

    Northwest A&F University, China

    2 publications · 183 citations

    2

    h-index

1–5 of 75

Institutions

38

  1. University of Iowa

    Iowa City, United States

    5 h-index

    7 publications

    129 citations

  2. Boehringer Ingelheim (Germany)

    Ingelheim, Germany

    2 h-index

    5 publications

    82 citations

  3. Northwest A&F University

    Yangling, China

    2 h-index

    12 publications

    1K citations

  4. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    3 publications

    299 citations

  5. Universidad de Navarra

    Pamplona, Spain

    2 h-index

    2 publications

    34 citations

  6. Dalian Institute of Chemical Physics

    Dalian, China

    2 h-index

    3 publications

    299 citations

  7. Pfizer (United Kingdom)

    Tadworth, United Kingdom

    2 h-index

    5 publications

    610 citations

  8. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    1 h-index

    1 publications

    14 citations

1–8 of 38

Venues

  1. Journal of Pharmaceutical Sciences

    5 publications · 102 citations

    5

    h-index

  2. CPT Pharmacometrics & Systems Pharmacology

    PSP · 3 publications · 65 citations

    3

    h-index

  3. Journal of Ethnopharmacology

    3 publications · 203 citations

    3

    h-index

  4. Psychopharmacology

    1 publications · 17 citations

    1

    h-index

  5. European Journal of Pharmaceutical Sciences

    1 publications · 17 citations

    1

    h-index

1–5