Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Comparison of four basic models of indirect pharmacodynamic responses

Natalie Dayneka, Varun Garg, William J. Jusko · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 811 citations

Medicine, Pharmacokinetics, Pharmacology +14

Predictive Pharmacokinetic-Pharmacodynamic Modeling of Tumor Growth Kinetics in Xenograft Models after Administration of Anticancer Agents

Monica Simeoni, Paolo Magni, Cristiano Cammia et al. · Cancer Research · 2004 · 499 citations · Full text

Medicine, Oncology, Pharmacology +16

Comparative Preclinical and Clinical Pharmacokinetics of a Cremophor-Free, Nanoparticle Albumin-Bound Paclitaxel (ABI-007) and Paclitaxel Formulated in Cremophor (Taxol)

Alex Sparreboom, Charity D. Scripture, Vuong Trieu et al. · Clinical Cancer Research · 2005 · 496 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Cremophor EL-mediated alteration of paclitaxel distribution in human blood: clinical pharmacokinetic implications.

Alex Sparreboom, Lia van Zuylen, Eric Brouwer et al. · PubMed · 1999 · 340 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16