Concepedia

Pharmacodynamic Modeling

Pharmacodynamic Modeling is a quantitative, typically mathematical, modeling approach in pharmacology that characterizes and predicts the relationship between drug exposure and the magnitude and time course of biological or clinical effects, often by parameterizing mechanisms of drug action and system response.

1.5K

Publications

92.7K

Citations

5K

Authors

1.5K

Institutions

Publications per year

2017–2026

355

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Children

Publications

1.5K

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

, , +16

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

, , +15

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

Yong Zhang, Meirong Huo, Jianping Zhou et al. · Computer Methods and Programs in Biomedicine · 2010 · 2.1K citations

, , +7

Manual of pharmacologic calculations with computer programs

International Journal of Biochemistry · 1988 · 1.5K citations

, , +12

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

, , +17

1–5 of 1.5K

Authors

5K

  1. LB
    Lewis B. Sheiner

    University of California, San Francisco, United States

    25 publications · 3.4K citations

    22

    h-index

  2. WJ
    William J. Jusko

    University at Buffalo, State University of New York, United States

    22 publications · 2.1K citations

    18

    h-index

  3. MD
    Meindert Danhof

    Leiden University, Netherlands

    23 publications · 854 citations

    17

    h-index

  4. MO
    Mats O. Karlsson

    Uppsala University, Sweden

    20 publications · 1.7K citations

    15

    h-index

  5. WK
    Wojciech Krzyżański

    University at Buffalo, State University of New York, United States

    16 publications · 621 citations

    14

    h-index

1–5 of 5K

Institutions

1.5K

  1. University at Buffalo, State University of New York

    Buffalo, United States

    36 h-index

    184 publications

    12.5K citations

  2. Uppsala University

    Uppsala, Sweden

    32 h-index

    193 publications

    13.3K citations

  3. University of California, San Francisco

    San Francisco, United States

    30 h-index

    121 publications

    19.2K citations

  4. Roche (Switzerland)

    Basel, Switzerland

    26 h-index

    85 publications

    4K citations

  5. Inserm

    Paris, France

    26 h-index

    114 publications

    4.3K citations

  6. Center for Drug Evaluation and Research

    Silver Spring, United States

    25 h-index

    168 publications

    10.8K citations

  7. University of Manchester

    Manchester, United Kingdom

    25 h-index

    77 publications

    4.3K citations

  8. Pfizer (United States)

    New York, United States

    24 h-index

    107 publications

    5.2K citations

1–8 of 1.5K

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 78 publications · 4.5K citations

    37

    h-index

  2. CPT Pharmacometrics & Systems Pharmacology

    PSP · 73 publications · 6.1K citations

    35

    h-index

  3. Journal of Pharmaceutical Sciences

    71 publications · 3.1K citations

    32

    h-index

  4. Journal of Pharmacokinetics and Biopharmaceutics

    56 publications · 3.6K citations

    31

    h-index

  5. Clinical Pharmacology & Therapeutics

    CPT · 51 publications · 4.4K citations

    30

    h-index

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