Paul Talalay

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

Ting‐Chao Chou, Paul Talalay · Advances in Enzyme Regulation · 1984 · 7.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Albena T. Dinkova‐Kostova, W. David Holtzclaw, Robert N. Cole et al. · Proceedings of the National Academy of Sciences · 2002 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

Yuesheng Zhang, Paul Talalay, C G Cho et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations

Life Sciences, Biochemistry, Toxicology +16

Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

Jed W. Fahey, Yuesheng Zhang, Paul Talalay · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations · Full text

Life Sciences, Plant Biology, Plant Sciences +14

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Life Sciences, Molecular Biology, Oncology +17