Patrick M. Dolan

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in <i>nrf2</i> transcription factor-deficient mice

Minerva Ramos‐Gómez, Mi-Kyoung Kwak, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Pathology, Cancer Biology, Redox Biology +21

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of<i>Helicobacter pylori</i>and prevents benzo[<i>a</i>]pyrene-induced stomach tumors

Jed W. Fahey, X. Haristoy, Patrick M. Dolan et al. · Proceedings of the National Academy of Sciences · 2002 · 788 citations · Full text

Gastroenterology, Pathology, Antimicrobial Chemotherapy +16

Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide

Soona Shin, Junko Wakabayashi, Melinda S. Yates et al. · European Journal of Pharmacology · 2009 · 273 citations · Full text

Obesity, Metabolic Syndrome, High-fat Diet-induced Obesity +11

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

Melinda S. Yates, Quynh T. Tran, Patrick M. Dolan et al. · Carcinogenesis · 2009 · 261 citations · Full text

Mechanism of protection against aflatoxin tumorigenicity in rats fed 5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione (oltipraz) and related 1,2-dithiol-3-thiones and 1,2-dithiol-3-ones.

Thomas W. Kensler, Patricia A. Egner, Patrick M. Dolan et al. · PubMed · 1987 · 242 citations

Chemoprevention Strategy, Pharmacotherapy, Aflatoxin Tumorigenicity +17