Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

Nobunao Wakabayashi, Ken Itoh, Junko Wakabayashi, +10

Nature Genetics

Reductive StressGenome InstabilityDevelopmental BiologyGenetic DisorderGenetics +7

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

Junko Wakabayashi, Zhongyan Zhang, Nobunao Wakabayashi, +5

The Journal of Cell Biology

MitophagyOrganelle DynamicBrain DevelopmentCell DeathMitochondrial Biology +23

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

Ken Nakamura, Venu M. Nemani, Farnaz Azarbal, +13

Journal of Biological Chemistry

Molecular BiologyMitochondrial BiologyMitochondrial FissionMembrane FusionOther Organelles +20

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

Takafumi Suzuki, Akira Kobayashi, Junko Wakabayashi, +3

Molecular and Cellular Biology

Molecular BiologyRedox BiologyOxidative StressTranscriptional RegulationProtein Expression +20

Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide

Soona Shin, Junko Wakabayashi, Melinda S. Yates, +7

European Journal of Pharmacology

ObesityMetabolic SyndromeHigh-fat Diet-induced ObesitySynthetic Triterpenoid Cddo-imidazolideBiochemistry +9

Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis

Shosei Yoshida, Ayumi Takakura, Kazuyuki Ohbo, +5

Developmental Biology

SpermatogenesisEarliest StagesFertilityGeneticsReproductive Biology +15

Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage

Yusuke Kageyama, Zhongyan Zhang, Ricardo H. Roda, +7

The Journal of Cell Biology

MitophagyOxidative DamageCell DeathMitochondrial ShapeMitochondrial Biology +19

Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration

Nobunao Wakabayashi, Soona Shin, Stephen L. Slocum, +7

Science Signaling

The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells

Zhongyan Zhang, Nobunao Wakabayashi, Junko Wakabayashi, +12

Molecular Biology of the Cell

Cell DeathCellular PhysiologyInsulin SignalingOxidative StressBeta Cells +22

Comparative pharmacokinetics of oxytetracycline in eel and its fate in a closed aquatic environment

Ryuji Ueno, Akiko Kinoshita, Junko Wakabayashi

Aquaculture

Closed Aquatic EnvironmentMedicineAquaculturePhysiologyToxicology +4