Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases

Analyzing real-time PCR data by the comparative CT method

Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols · 2008 · 26.7K citations

Public Health, Biostatistics, Biomedical Signal Processing +3

Drug—target network

Muhammed A. Yıldırım, K.-I. Goh, Michael E. Cusick et al. · Nature Biotechnology · 2007 · 1.7K citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

Marek Dráb, Paul Verkade, Marlies Elger et al. · Science · 2001 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +17

Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial

Philip Home, Stuart Pocock, Henning Beck‐Nielsen et al. · The Lancet · 2009 · 1.4K citations

Medicine, Pharmacology, Pharmacotherapy +17

Property Distributions:  Differences between Drugs, Natural Products, and Molecules from Combinatorial Chemistry

Miklós Fehér, Jonathan M. Schmidt · Journal of Chemical Information and Computer Sciences · 2002 · 921 citations

Pharmacy, Chemistry, Medicinal Chemistry +16