Neil Benson

Oscillations in NF-κB Signaling Control the Dynamics of Gene Expression

David E. Nelson, Adaoha Ihekwaba, Malcolm C. Elliott et al. · Science · 2004 · 1.2K citations

Life Sciences, Cell Biology, Molecular Biology +17

Systems Pharmacology: Bridging Systems Biology and Pharmacokinetics-Pharmacodynamics (PKPD) in Drug Discovery and Development

Piet H. van der Graaf, Neil Benson · Pharmaceutical Research · 2011 · 242 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Model-Based Drug Development: A Rational Approach to Efficiently Accelerate Drug Development

Peter A. Milligan, Marcy Brown, B Marchant et al. · Clinical Pharmacology & Therapeutics · 2013 · 236 citations

Medicine, Pharmacology, Clinical Pharmacology +10

Sensitivity analysis of parameters controlling oscillatory signalling in the NF-κB pathway: the roles of IKK and IκBα

Adaoha Ihekwaba, Neil Benson, Douglas B. Kell et al. · Systems Biology · 2004 · 146 citations

Life Sciences, Cell Biology, Molecular Biology +14

First-in-human phase I study of the bromodomain and extraterminal motif inhibitor BAY 1238097: emerging pharmacokinetic/pharmacodynamic relationship and early termination due to unexpected toxicity

Sophie Postel‐Vinay, Karin H. Herbschleb, Christophe Massard et al. · European Journal of Cancer · 2019 · 104 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12