Concepedia

Signal Peptide Optimization

Signal Peptide Optimization is a methodological approach in molecular engineering that systematically refines the amino acid sequence of signal peptides to enhance the efficiency and fidelity of protein translocation and surface display in yeast expression systems.

115

Publications

9.6K

Citations

656

Authors

197

Institutions

Publications per year

2017–2026

61

Parents

Publications

115

SignalP 5.0 improves signal peptide predictions using deep neural networks

José Juan Almagro Armenteros, Konstantinos D. Tsirigos, Casper Kaae Sønderby et al. · Nature Biotechnology · 2019 · 4.7K citations · Full text

, , +12

Systematic Screening of All Signal Peptides from Bacillus subtilis: A Powerful Strategy in Optimizing Heterologous Protein Secretion in Gram-positive Bacteria

Ulf Brockmeier, Michael Caspers, Roland Freudl et al. · Journal of Molecular Biology · 2006 · 284 citations

, , +17

Directed Evolution of Unspecific Peroxygenase from Agrocybe aegerita

Patricia Molina‐Espeja, Eva Garcia‐Ruiz, David González-Pérez et al. · Applied and Environmental Microbiology · 2014 · 255 citations · Full text

, , +13

Protein secretion in Lactococcus lactis: an efficient way to increase the overall heterologous protein production

Yves Le Loir, Vasco Azevedo, Sérgio C. Oliveira et al. · Microbial Cell Factories · 2005 · 214 citations · Full text

, , +17

Optimized signal peptides for the development of high expressing CHO cell lines

Christoph Zehe, Juergen Bode · Biotechnology and Bioengineering · 2012 · 171 citations

, , +17

1–5 of 115

Authors

656

  1. YG
    Younes Ghasemi

    Shiraz University of Medical Sciences, Iran

    6 publications · 107 citations

    6

    h-index

  2. ZM
    Zohreh Mostafavi‐Pour

    Shiraz University of Medical Sciences, Iran

    4 publications · 59 citations

    4

    h-index

  3. MH
    Mohammad Hossein Morowvat

    Shiraz University of Medical Sciences, Iran

    4 publications · 80 citations

    4

    h-index

  4. RM
    Rosli Md Illias

    University of Technology Malaysia, Malaysia

    4 publications · 112 citations

    4

    h-index

  5. GR
    Garshasb Rigi

    National Institute of Genetic Engineering and Biotechnology, Iran

    3 publications · 68 citations

    3

    h-index

1–5 of 656

Institutions

197

  1. Shiraz University of Medical Sciences

    Shiraz, Iran

    8 h-index

    46 publications

    853 citations

  2. Jiangnan University

    Wuxi, China

    6 h-index

    31 publications

    1.1K citations

  3. University of Technology Malaysia

    Johor Bahru, Malaysia

    4 h-index

    10 publications

    267 citations

  4. National Institute of Genetic Engineering and Biotechnology

    Tehran, Iran

    4 h-index

    18 publications

    357 citations

  5. Zhejiang University

    Hangzhou, China

    3 h-index

    12 publications

    249 citations

  6. Chinese Academy of Agricultural Sciences

    Beijing, China

    3 h-index

    13 publications

    824 citations

  7. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    20 publications

    1.1K citations

  8. Département Génétique Animale

    Castanet-Tolosan, France

    3 h-index

    19 publications

    3.2K citations

1–8 of 197

Venues

  1. Microbial Cell Factories

    8 publications · 615 citations

    8

    h-index

  2. Journal of Microbiology and Biotechnology

    6 publications · 104 citations

    6

    h-index

  3. Applied Microbiology and Biotechnology

    6 publications · 199 citations

    6

    h-index

  4. PLoS ONE

    5 publications · 298 citations

    5

    h-index

  5. Protein Expression and Purification

    5 publications · 123 citations

    5

    h-index

1–5