Concepedia

Off-target Editing Analysis

Off-Target Editing Analysis is a methodological framework in genome engineering that identifies and quantifies unintended modifications introduced by base editing tools at genomic sites other than the intended target locus.

43

Publications

2.9K

Citations

323

Authors

136

Institutions

Publications per year

2017–2026

37

Parents

Publications

43

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

Thomas J. Cradick, Eli J. Fine, Christopher J. Antico et al. · Nucleic Acids Research · 2013 · 604 citations · Full text

, , +15

A large-scale whole-genome sequencing analysis reveals highly specific genome editing by both Cas9 and Cpf1 (Cas12a) nucleases in rice

Xu Tang, Guanqing Liu, Jianping Zhou et al. · Genome biology · 2018 · 307 citations · Full text

, , +15

GT-Scan: identifying unique genomic targets

Aidan R. O’Brien, Timothy L. Bailey · Bioinformatics · 2014 · 155 citations · Full text

, , +16

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Puping Liang, Xiaowei Xie, Shengyao Zhi et al. · Nature Communications · 2019 · 144 citations · Full text

, , +17

Enhancement of prime editing via xrRNA motif-joined pegRNA

Guiquan Zhang, Yao Liu, Shisheng Huang et al. · Nature Communications · 2022 · 116 citations · Full text

, , +17

1–5 of 43

Authors

323

  1. EZ
    Erwei Zuo

    Chinese Academy of Agricultural Sciences, China

    3 publications · 155 citations

    3

    h-index

  2. YQ
    Yiping Qi

    University of Maryland, College Park, United States

    3 publications · 378 citations

    3

    h-index

  3. YS
    Yidi Sun

    Chinese Academy of Sciences, China

    3 publications · 155 citations

    3

    h-index

  4. TZ
    Tao Zhang

    Yangzhou University, China

    3 publications · 378 citations

    3

    h-index

  5. GM
    George M. Church

    Harvard University, United States

    3 publications · 128 citations

    3

    h-index

1–5 of 323

Institutions

136

  1. Chinese Academy of Sciences

    Beijing, China

    5 h-index

    15 publications

    802 citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    14 publications

    676 citations

  3. Advanced Bioscience Laboratories (United States)

    Rockville, United States

    3 h-index

    3 publications

    378 citations

  4. Guangzhou Medical University

    Guangzhou, China

    3 h-index

    12 publications

    711 citations

  5. Inspire Institute

    Alexandria, United States

    3 h-index

    6 publications

    256 citations

  6. Agricultural Genomics Institute at Shenzhen

    Shenzhen, China

    3 h-index

    9 publications

    406 citations

  7. University of Maryland, College Park

    College Park, United States

    3 h-index

    7 publications

    773 citations

  8. Chinese Academy of Agricultural Sciences

    Beijing, China

    3 h-index

    8 publications

    374 citations

1–8 of 136

Venues

  1. Nature Communications

    10 publications · 670 citations

    10

    h-index

  2. Nucleic Acids Research

    3 publications · 649 citations

    3

    h-index

  3. Genome Research

    GR · 2 publications · 119 citations

    2

    h-index

  4. The CRISPR Journal

    2 publications · 63 citations

    2

    h-index

  5. Bioinformatics

    2 publications · 253 citations

    2

    h-index

1–5