Shengyao Zhi

Dual-AAV delivering split prime editor system for in vivo genome editing

Shengyao Zhi, Yuxi Chen, Guanglan Wu et al. · Molecular Therapy · 2021 · 168 citations · Full text

Life Sciences, Biotechnology, Genetics +16

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Puping Liang, Xiaowei Xie, Shengyao Zhi et al. · Nature Communications · 2019 · 144 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells

Yuxi Chen, Jiaqi Liu, Shengyao Zhi et al. · Nature Communications · 2020 · 64 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Development of Highly Efficient Dual‐AAV Split Adenosine Base Editor for In Vivo Gene Therapy

Yuxi Chen, Shengyao Zhi, Weiliang Liu et al. · Small Methods · 2020 · 57 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Single AAV-mediated CRISPR-Nme2Cas9 efficiently reduces mutant hTTR expression in a transgenic mouse model of transthyretin amyloidosis

Jinkun Wen, Tianqi Cao, Jinni Wu et al. · Molecular Therapy · 2021 · 24 citations · Full text

Life Sciences, Genetics, Molecular Biology +17