Aidan R. O’Brien

GT-Scan: identifying unique genomic targets

Aidan R. O’Brien, Timothy L. Bailey · Bioinformatics · 2014 · 155 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros et al. · Genome biology · 2019 · 109 citations · Full text

Life Sciences, Biotechnology, Genetics +13

High Activity Target-Site Identification Using Phenotypic Independent CRISPR-Cas9 Core Functionality

Daniel Reti, Aidan R. O’Brien, Robert Dunne et al. · The CRISPR Journal · 2018 · 55 citations

Life Sciences, Genetics, Molecular Genetics +13

Unlocking HDR-mediated nucleotide editing by identifying high-efficiency target sites using machine learning

Aidan R. O’Brien, Gaétan Burgio, Denis C. Bauer · Scientific Reports · 2019 · 48 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

VariantSpark: population scale clustering of genotype information

Aidan R. O’Brien, Neil Saunders, Yi Guo et al. · BMC Genomics · 2015 · 33 citations · Full text

Life Sciences, Bioinformatics, Genetics +15