Concepedia

Enzyme Selection

Enzyme Selection is a methodological construct in metabolic pathway engineering that involves the systematic identification and prioritization of specific enzymes based on catalytic efficiency, substrate specificity, and compatibility with host organisms to optimize synthetic pathway performance.

143

Publications

7.2K

Citations

592

Authors

221

Institutions

Publications per year

2017–2026

45

Parents

Publications

143

Automated Design of Efficient and Functionally Diverse Enzyme Repertoires

Olga Khersonsky, Rosalie Lipsh‐Sokolik, Ziv Avizemer et al. · Molecular Cell · 2018 · 303 citations · Full text

, , +14

Network Context and Selection in the Evolution to Enzyme Specificity

Hojung Nam, Nathan E. Lewis, Joshua A. Lerman et al. · Science · 2012 · 298 citations · Full text

, , +17

LIMITS OF ADAPTATION: THE EVOLUTION OF SELECTIVE NEUTRALITY

Daniel L. Hartl, Daniel E. Dykhuizen, Antony M. Dean · Genetics · 1985 · 292 citations · Full text

, , +13

Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme

Nobuhiko Tokuriki, Colin J. Jackson, Livnat Afriat‐Jurnou et al. · Nature Communications · 2012 · 263 citations · Full text

, , +12

Analysis of Selection on Enzyme Polymorphisms

Walter F. Eanes · Annual Review of Ecology and Systematics · 1999 · 231 citations

, , +13

1–5 of 143

Authors

592

  1. DL
    Daniel L. Hartl

    Harvard University, United States

    5 publications · 568 citations

    5

    h-index

  2. DH
    Donald Hilvert

    ETH Zurich, Switzerland

    4 publications · 221 citations

    4

    h-index

  3. HL
    Han Li

    University of California, Irvine, United States

    3 publications · 101 citations

    3

    h-index

  4. EJ
    Edward J. King

    University of California, Irvine, United States

    3 publications · 101 citations

    3

    h-index

  5. PK
    Peter Kast

    ETH Zurich, Switzerland

    3 publications · 200 citations

    3

    h-index

1–5 of 592

Institutions

221

  1. Harvard University

    Cambridge, United States

    5 h-index

    11 publications

    591 citations

  2. University of California, Irvine

    Irvine, United States

    5 h-index

    20 publications

    824 citations

  3. ETH Zurich

    Zurich, Switzerland

    4 h-index

    15 publications

    582 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    17 publications

    801 citations

  5. University of Minnesota

    Minneapolis, United States

    4 h-index

    12 publications

    354 citations

  6. Jiangnan University

    Wuxi, China

    4 h-index

    18 publications

    366 citations

  7. Washington University in St. Louis

    St Louis, United States

    4 h-index

    7 publications

    1K citations

  8. University of Bristol

    Bristol, United Kingdom

    3 h-index

    8 publications

    459 citations

1–8 of 221

Venues

  1. ACS Synthetic Biology

    6 publications · 289 citations

    6

    h-index

  2. PLoS ONE

    5 publications · 154 citations

    5

    h-index

  3. Applied and Environmental Microbiology

    AEM · 4 publications · 435 citations

    4

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 254 citations

    4

    h-index

  5. Genetics

    4 publications · 577 citations

    4

    h-index

1–5