Concepedia

Metabolic Pathway Engineering

Metabolic Pathway Engineering is the academic concept of a targeted modification strategy within biocatalysis that involves the rational design and systematic optimization of enzymatic sequences in cellular metabolism to achieve enhanced biosynthetic capabilities or metabolic fluxes distinct from natural configurations.

7.8K

Publications

484.2K

Citations

25.2K

Authors

3.2K

Institutions

Publications per year

2017–2026

3.8K

Parents

Children

Publications

7.8K

Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

Shota Atsumi, Taizo Hanai, James C. Liao · Nature · 2008 · 2K citations

, , +14

A protocol for generating a high-quality genome-scale metabolic reconstruction

Ines Thiele, Bernhard Ø. Palsson · Nature Protocols · 2010 · 1.9K citations · Full text

, , +11

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

Vincent J. J. Martin, Douglas J. Pitera, Sydnor T. Withers et al. · Nature Biotechnology · 2003 · 1.7K citations

, , +14

Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in <i>Escherichia coli</i>

Parayil Kumaran Ajikumar, Wenhai Xiao, Keith E. J. Tyo et al. · Science · 2010 · 1.6K citations

, , +17

Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

Anthony P. Burgard, Priti Pharkya, Costas D. Maranas · Biotechnology and Bioengineering · 2003 · 1.3K citations

, , +17

1–5 of 7.8K

Authors

25.2K

  1. JD
    Jay D. Keasling

    University of California, Berkeley, United States

    129 publications · 17.9K citations

    67

    h-index

  2. JN
    Jens Nielsen

    Chalmers University of Technology, Sweden

    97 publications · 11.6K citations

    62

    h-index

  3. SY
    Sang Yup Lee

    Korea Advanced Institute of Science and Technology, South Korea

    116 publications · 12.4K citations

    59

    h-index

  4. GS
    Gregory Stephanopoulos

    Massachusetts Institute of Technology, United States

    57 publications · 10.2K citations

    42

    h-index

  5. GD
    Guocheng Du

    Jiangnan University, China

    90 publications · 4.8K citations

    41

    h-index

1–5 of 25.2K

Institutions

3.2K

  1. Chinese Academy of Sciences

    Beijing, China

    78 h-index

    2.4K publications

    137.4K citations

  2. University of California, Berkeley

    Berkeley, United States

    78 h-index

    526 publications

    66.8K citations

  3. Technical University of Denmark

    Kongens Lyngby, Denmark

    74 h-index

    737 publications

    73.7K citations

  4. Lawrence Berkeley National Laboratory

    Berkeley, United States

    73 h-index

    855 publications

    78.3K citations

  5. Novo Nordisk Foundation

    Copenhagen, Denmark

    66 h-index

    579 publications

    59K citations

  6. Joint BioEnergy Institute

    Emeryville, United States

    64 h-index

    864 publications

    80.3K citations

  7. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    64 h-index

    505 publications

    50.5K citations

  8. Jiangnan University

    Wuxi, China

    61 h-index

    2K publications

    80.8K citations

1–8 of 3.2K

Venues

  1. Metabolic Engineering

    532 publications · 51.1K citations

    123

    h-index

  2. Biotechnology and Bioengineering

    334 publications · 22.9K citations

    89

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 138 publications · 22.7K citations

    87

    h-index

  4. Applied and Environmental Microbiology

    AEM · 274 publications · 22.2K citations

    85

    h-index

  5. Nature Communications

    193 publications · 19.3K citations

    82

    h-index

1–5