Concepedia

Pathway Balancing

Pathway Balancing is a metabolic engineering strategy that optimizes the relative expression and activity levels of pathway enzymes to achieve coordinated flux distribution and minimize metabolic burden within a synthetic or engineered metabolic pathway in microbial cell factories.

14

Publications

974

Citations

88

Authors

28

Institutions

Publications per year

2017–2026

10

Parents

Publications

14

ePathOptimize: A Combinatorial Approach for Transcriptional Balancing of Metabolic Pathways

J. Andrew Jones, Victoria R. Vernacchio, Daniel M. Lachance et al. · Scientific Reports · 2015 · 155 citations · Full text

, , +17

Segregating metabolic processes into different microbial cells accelerates the consumption of inhibitory substrates

Elin Lilja, David R. Johnson · The ISME Journal · 2016 · 126 citations · Full text

, , +16

Development of a growth coupled and multi-layered dynamic regulation network balancing malonyl-CoA node to enhance (2S)-naringenin biosynthesis in Escherichia coli

Shenghu Zhou, Shuo‐Fu Yuan, Priya H. Nair et al. · Metabolic Engineering · 2021 · 118 citations

, , +17

Metabolomics-driven approach to solving a CoA imbalance for improved 1-butanol production in Escherichia coli

Toshiyuki Ohtake, Sammy Pontrelli, Walter A. Laviña et al. · Metabolic Engineering · 2017 · 107 citations

, , +17

Fine‐tuning the (2<i>S</i>)‐naringenin synthetic pathway using an iterative high‐throughput balancing strategy

Shenghu Zhou, Yunbin Lyu, Huazhong Li et al. · Biotechnology and Bioengineering · 2019 · 102 citations

, , +17

1–5 of 14

Authors

88

  1. MK
    Mattheos Koffas

    Rensselaer Polytechnic Institute, United States

    2 publications · 257 citations

    2

    h-index

  2. RJ
    Robert J. Linhardt

    Rensselaer Polytechnic Institute, United States

    2 publications · 186 citations

    2

    h-index

  3. SZ
    Shenghu Zhou

    Jiangnan University, China

    2 publications · 220 citations

    2

    h-index

  4. JZ
    Jingwen Zhou

    Jiangnan University, China

    2 publications · 220 citations

    2

    h-index

  5. YY
    Yuan Yao

    Purdue University West Lafayette, United States

    1 publications · 26 citations

    1

    h-index

1–5 of 88

Institutions

28

  1. Rensselaer Polytechnic Institute

    Troy, United States

    3 h-index

    13 publications

    1.7K citations

  2. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    5 publications

    178 citations

  3. Jiangnan University

    Wuxi, China

    2 h-index

    7 publications

    762 citations

  4. Zhejiang University of Technology

    Hangzhou, China

    2 h-index

    15 publications

    420 citations

  5. Zhejiang University

    Hangzhou, China

    2 h-index

    8 publications

    440 citations

  6. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    5 publications

    178 citations

  7. ETH Zurich

    Zurich, Switzerland

    1 h-index

    1 publications

    126 citations

  8. Pusan National University

    Busan, South Korea

    1 h-index

    5 publications

    150 citations

1–8 of 28

Venues

  1. Metabolic Engineering

    3 publications · 248 citations

    3

    h-index

  2. Biotechnology and Bioengineering

    3 publications · 211 citations

    3

    h-index

  3. ACS Synthetic Biology

    2 publications · 57 citations

    2

    h-index

  4. Journal of Biotechnology

    1 publications · 30 citations

    1

    h-index

  5. Scientific Reports

    1 publications · 155 citations

    1

    h-index

1–5