Pathway Design

Pathway Design is a metabolic engineering strategy that involves the systematic identification, construction, and optimization of biochemical reaction sequences to enable or enhance the production of specific metabolites within a host organism.

243

Publications

18.1K

Citations

1.1K

Authors

371

Institutions

Publications per year

2017–2026

120

Variants

Metabolic Pathway Design

Parents

Metabolic Engineering

Children

Biosynthetic Pathway ConstructionCofactor BalancingComputational Pathway DesignEnzyme Cascade DesignEnzyme SelectionFeedback RegulationFlux ControlFlux RedirectionGene Cluster DesignGenome-scale Pathway Design

Publications

243

Prediction of Organic Reaction Outcomes Using Machine Learning

Connor W. Coley, Regina Barzilay, Tommi Jaakkola et al. · ACS Central Science · 2017 · 823 citations · Full text

Engineering, Chemical Engineering, Computer Science +15

Flavonoids and isoflavonoids – a gold mine for metabolic engineering

Richard A. F. Dixon, Christopher L. Steele · Trends in Plant Science · 1999 · 715 citations

Engineering, Biochemistry, Biotechnology +14

Cell-free chemoenzymatic starch synthesis from carbon dioxide

Tao Cai, Hongbing Sun, Jing Qiao et al. · Science · 2021 · 605 citations

Engineering, Biochemistry, Biotechnology +17

OptStrain: A computational framework for redesign of microbial production systems

Priti Pharkya, Anthony P. Burgard, Costas D. Maranas · Genome Research · 2004 · 498 citations · Full text

Engineering, Biotechnology, Chemical Engineering +17

Metabolic engineering and pathway construction for biotechnological production of relevant polyhydroxyalkanoates in microorganisms

Alexander Steinbüchel, Tina Lütke‐Eversloh · Biochemical Engineering Journal · 2003 · 462 citations

Life Sciences, Biochemistry, Biotechnology +17

1–5 of 243

Authors

1.1K

JF
Jean‐Loup Faulon
University of Manchester, United Kingdom
9 publications · 879 citations
9
h-index
PC
Pablo Carbonell
University of Manchester, United Kingdom
8 publications · 813 citations
8
h-index
EM
Enrique Meléndez‐Hevia
Universidad de La Laguna, Spain
7 publications · 578 citations
7
h-index
CA
Christopher A. Voigt
Massachusetts Institute of Technology, United States
6 publications · 462 citations
6
h-index
SY
Sang Yup Lee
Korea Advanced Institute of Science and Technology, South Korea
6 publications · 296 citations
6
h-index

1–5 of 1.1K

Institutions

371

1–8 of 371

Venues

ACS Synthetic Biology
22 publications · 1.3K citations
19
h-index
Metabolic Engineering
21 publications · 1.5K citations
19
h-index
Nature Communications
13 publications · 1.2K citations
13
h-index
Bioinformatics
10 publications · 556 citations
10
h-index
Nucleic Acids Research
9 publications · 533 citations
9
h-index

1–5