Concepedia

Knockout Strategy Design

Knockout Strategy Design is a computational or experimental framework within metabolic pathway engineering that specifies the systematic identification and elimination of specific gene functions to achieve a desired metabolic phenotype while minimizing unintended physiological consequences.

25

Publications

821

Citations

149

Authors

57

Institutions

Publications per year

2017–2026

10

Parents

Publications

25

Forebrain HCN1 Channels Contribute to Hypnotic Actions of Ketamine

Cheng Zhou, Jennifer E. Douglas, Natasha N. Kumar et al. · Anesthesiology · 2013 · 85 citations · Full text

, , +16

Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons

Julien Vermot, Brigitte Schuhbaur, Hervé Le Mouellic et al. · Development · 2005 · 81 citations

, , +13

FastPros: screening of reaction knockout strategies for metabolic engineering

Satoshi Ohno, Hiroshi Shimizu, Chikara Furusawa · Bioinformatics · 2013 · 54 citations · Full text

, , +16

Adaptive bi-level programming for optimal gene knockouts for targeted overproduction under phenotypic constraints

Shaogang Ren, Bo Zeng, Xiaoning Qian · BMC Bioinformatics · 2013 · 53 citations · Full text

, , +15

Glycerol-Mediated Repression of Glucose Metabolism and Glycerol Kinase as the Sole Route of Glycerol Catabolism in the Haloarchaeon <i>Haloferax volcanii</i>

Katherine E. Sherwood, David José Cano, Julie A. Maupin‐Furlow · Journal of Bacteriology · 2009 · 50 citations

, , +14

1–5 of 25

Authors

149

  1. CR
    Christina Rode

    Leibniz University Hannover, Germany

    1 publications · 44 citations

    1

    h-index

  2. HP
    Hexiang Peng

    Peking University, China

    1 publications · 25 citations

    1

    h-index

  3. MD
    Michalitsa Diakatou

    Université de Montpellier, France

    1 publications · 38 citations

    1

    h-index

  4. SO
    Satoshi Ohno

    Kanazawa University, Japan

    1 publications · 54 citations

    1

    h-index

  5. CH
    Christopher H.K. Cheng

    Chinese University of Hong Kong, Hong Kong SAR China

    1 publications · 15 citations

    1

    h-index

1–5 of 149

Institutions

57

  1. New York University

    New York, United States

    2 h-index

    8 publications

    146 citations

  2. Sichuan University

    Chengdu, China

    2 h-index

    4 publications

    206 citations

  3. Inserm

    Paris, France

    2 h-index

    13 publications

    795 citations

  4. Royal Liverpool and Broadgreen University Hospital NHS Trust

    Liverpool, United Kingdom

    1 h-index

    3 publications

    72 citations

  5. Tata Institute of Fundamental Research

    Mumbai, India

    1 h-index

    2 publications

    28 citations

  6. Institut Pasteur

    Paris, France

    1 h-index

    2 publications

    162 citations

  7. GlaxoSmithKline (Ireland)

    Cork, Ireland

    1 h-index

    1 publications

    32 citations

  8. The University of Texas Southwestern Medical Center

    Dallas, United States

    1 h-index

    3 publications

    42 citations

1–8 of 57

Venues

  1. Bioinformatics

    3 publications · 86 citations

    3

    h-index

  2. Development

    2 publications · 125 citations

    2

    h-index

  3. BMC Bioinformatics

    2 publications · 69 citations

    2

    h-index

  4. Drug Discovery Today

    1 publications · 32 citations

    1

    h-index

  5. PLoS ONE

    1 publications · 18 citations

    1

    h-index

1–5