Peter Kast

An evolution-based model for designing chorismate mutase enzymes

William P. Russ, Matteo Figliuzzi, Christian Stocker et al. · Science · 2020 · 340 citations

Engineering, Quantitative Complementation Assay, Molecular Biology +19

Evolution of a designed retro-aldolase leads to complete active site remodeling

Lars Giger, S. Caner, Richard Obexer et al. · Nature Chemical Biology · 2013 · 286 citations · Full text

Biosynthesis, Engineering, Aldo-keto Reductase +10

Investigating and Engineering Enzymes by Genetic Selection

Sean V. Taylor, Peter Kast, Donald Hilvert · Angewandte Chemie International Edition · 2001 · 205 citations

Engineering Enzymes, Engineering, Genetics +20

Robust design and optimization of retroaldol enzymes

Eric A. Althoff, Ling Wang, Lin Jiang et al. · Protein Science · 2012 · 184 citations

Exploring the active site of chorismate mutase by combinatorial mutagenesis and selection: the importance of electrostatic catalysis.

Peter Kast, M. Asif-Ullah, Ning Jiang et al. · Proceedings of the National Academy of Sciences · 1996 · 158 citations · Full text

Engineering, Molecular Biology, Escherichia Coli +16