Eric A. Althoff

Kemp elimination catalysts by computational enzyme design

Daniela Röthlisberger, Olga Khersonsky, Andrew M. Wollacott et al. · Nature · 2008 · 1.3K citations

Engineering, Chemical Engineering, Chemistry +14

De Novo Computational Design of Retro-Aldol Enzymes

Lin Jiang, Eric A. Althoff, Fernando R. Clemente et al. · Science · 2008 · 1.2K citations

Life Sciences, Biochemistry, Computational Design +17

New algorithms and an in silico benchmark for computational enzyme design

Alexandre Zanghellini, Lin Jiang, Andrew M. Wollacott et al. · Protein Science · 2006 · 365 citations · Full text

Engineering, Bioinformatics, Biocatalysis +15

Robust design and optimization of retroaldol enzymes

Eric A. Althoff, Ling Wang, Lin Jiang et al. · Protein Science · 2012 · 184 citations

Engineering, Biochemistry, Biotechnology +16

Structural Analyses of Covalent Enzyme–Substrate Analog Complexes Reveal Strengths and Limitations of De Novo Enzyme Design

Ling Wang, Eric A. Althoff, Jill M. Bolduc et al. · Journal of Molecular Biology · 2011 · 64 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14