Richard Obexer

Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

Richard Obexer, Xavier Garrabou, Peer R. E. Mittl et al. · Nature Chemistry · 2016 · 319 citations

Life Sciences, Biochemistry, Chemistry +14

Evolution of a designed retro-aldolase leads to complete active site remodeling

Lars Giger, S. Caner, Richard Obexer et al. · Nature Chemical Biology · 2013 · 293 citations · Full text

Life Sciences, Biochemistry, Biotechnology +12

A designed photoenzyme for enantioselective [2+2] cycloadditions

Jonathan S. Trimble, Rebecca Crawshaw, Florence J. Hardy et al. · Nature · 2022 · 208 citations · Full text

Natural Sciences, Biochemistry, Chemistry +6

Ultrahigh-throughput screening enables efficient single-round oxidase remodelling

Aaron Debon, Moritz Pott, Richard Obexer et al. · Nature Catalysis · 2019 · 96 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

An enzyme cascade enables production of therapeutic oligonucleotides in a single operation

Eddie Moody, Richard Obexer, F. Nickl et al. · Science · 2023 · 76 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +16