Richard Obexer

Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase

Richard Obexer, Xavier Garrabou, Peer R. E. Mittl et al. · Nature Chemistry · 2016 · 316 citations

Active Artificial Aldolase, Engineering, Biochemistry +8

Evolution of a designed retro-aldolase leads to complete active site remodeling

Lars Giger, S. Caner, Richard Obexer et al. · Nature Chemical Biology · 2013 · 286 citations · Full text

Biosynthesis, Engineering, Aldo-keto Reductase +10

A designed photoenzyme for enantioselective [2+2] cycloadditions

Jonathan S. Trimble, Rebecca Crawshaw, Florence J. Hardy et al. · Nature · 2022 · 190 citations · Full text

Organic Chemistry, Chemistry, Photochemistry +1

Ultrahigh-throughput screening enables efficient single-round oxidase remodelling

Aaron Debon, Moritz Pott, Richard Obexer et al. · Nature Catalysis · 2019 · 96 citations · Full text

Biochemistry, Natural Sciences, Biocatalysis +3

Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting

Richard Obexer, Moritz Pott, Cathleen Zeymer et al. · Protein Engineering Design and Selection · 2016 · 67 citations · Full text