Rebecca Crawshaw

A designed photoenzyme for enantioselective [2+2] cycloadditions

Jonathan S. Trimble, Rebecca Crawshaw, Florence J. Hardy et al. · Nature · 2022 · 208 citations · Full text

Natural Sciences, Biochemistry, Chemistry +6

Design and evolution of an enzyme with a non-canonical organocatalytic mechanism

Ashleigh J. Burke, Sarah L. Lovelock, Amina Frese et al. · Nature · 2019 · 168 citations

Life Sciences, Biochemistry, Biotechnology +12

Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction

Rebecca Crawshaw, Amy E. Crossley, Linus O. Johannissen et al. · Nature Chemistry · 2021 · 107 citations · Full text

Engineering, Biotechnology, Chemistry +12

Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site

Indrek Kalvet, Mary Ortmayer, Jingming Zhao et al. · Journal of the American Chemical Society · 2023 · 84 citations · Full text

Life Sciences, Biochemistry, Chemistry +17

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir

Ashleigh J. Burke, William R. Birmingham, Ying Zhuo et al. · Journal of the American Chemical Society · 2022 · 51 citations · Full text

Engineering, Biotechnology, Molecular Biology +17