A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model

Takehisa Kitazawa, Tomoyuki Igawa, Zenjiro Sampei, +31

Nature Medicine

InflammationImmunohematologyX RestoresFactors IxaGranulocyte +8

Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization

Tomoyuki Igawa, Shinya Ishii, Tatsuhiko Tachibana, +18

Nature Biotechnology

EngineeringMedicineImmunoengineeringImmunologyImmunodominance +10

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda, +16

PLoS ONE

Immunocytochemical TechniqueImmunologyPathologyImmunodominanceChemical Biology +21

TROY, a Newly Identified Member of the Tumor Necrosis Factor Receptor Superfamily, Exhibits a Homology with Edar and Is Expressed in Embryonic Skin and Hair Follicles

Tetsuo Kojima, Yoshihiro Morikawa, Neal G. Copeland, +4

Journal of Biological Chemistry

Molecular Cloning and Expression of Megakaryocyte Potentiating Factor cDNA

Tetsuo Kojima, Masayoshi Oh‐eda, Kunihiro Hattori, +4

Journal of Biological Chemistry

Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets

Atsushi Ohta, Mikimasa Tanada, Shojiro Shinohara, +44

Journal of the American Chemical Society

A signal sequence trap based on a constitutively active cytokine receptor

Tetsuo Kojima, Toshio Kitamura

Nature Biotechnology

CytokineSignal TransductionAutoimmune DiseaseImmunologyImmune Regulation +9

Entactin-2: A New Member of Basement Membrane Protein with High Homology to Entactin/Nidogen

Naoki Kimura, Tomoko Toyoshima, Tetsuo Kojima, +1

Experimental Cell Research

Protein SecretionProtein FunctionBiochemistryNatural SciencesMedicine +10

Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain

Keishi Fujio, Tetsuya Nosaka, Tetsuo Kojima, +8

Blood

A Novel Low-Density Lipoprotein Receptor-Related Protein Mediating Cellular Uptake of Apolipoprotein E-Enriched β-VLDL in Vitro^,

Takuya Sugiyama, Hidetoshi Kumagai, Yoshihiro Morikawa, +12

Biochemistry