Zenjiro Sampei

A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model

Takehisa Kitazawa, Tomoyuki Igawa, Zenjiro Sampei et al. · Nature Medicine · 2012 · 489 citations

Inflammation, Immunohematology, X Restores +10

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda et al. · PLoS ONE · 2013 · 313 citations · Full text

Immunocytochemical Technique, Immunology, Pathology +23

Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases

Taku Fukuzawa, Zenjiro Sampei, Kenta Haraya et al. · Scientific Reports · 2017 · 104 citations · Full text

Immunohematology, Immunology, Blood Cell +17

Anti-factor IXa/X bispecific antibody ACE910 prevents joint bleeds in a long-term primate model of acquired hemophilia A

Atsushi Muto, Kazutaka Yoshihashi, Minako Takeda et al. · Blood · 2014 · 92 citations · Full text

Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody

Zenjiro Sampei, Kenta Haraya, Tatsuhiko Tachibana et al. · PLoS ONE · 2018 · 56 citations · Full text