Takehisa Kitazawa

A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model

Takehisa Kitazawa, Tomoyuki Igawa, Zenjiro Sampei et al. · Nature Medicine · 2012 · 489 citations

Inflammation, Immunohematology, X Restores +10

G-protein-mediated Ca2+ sensitization of smooth muscle contraction through myosin light chain phosphorylation

Takehisa Kitazawa, Bruce D. Gaylinn, G H Denney et al. · Journal of Biological Chemistry · 1991 · 322 citations · Full text

G-protein-mediated Ca2+ Sensitization, Muscle Function, Engineering +20

Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity

Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda et al. · PLoS ONE · 2013 · 313 citations · Full text

Immunocytochemical Technique, Immunology, Pathology +23

Myosin light chain phosphatase activities and the effects of phosphatase inhibitors in tonic and phasic smooth muscle.

Meng Gong, Philip Cohen, Takehisa Kitazawa et al. · Journal of Biological Chemistry · 1992 · 211 citations · Full text

Muscle Function, Cytoskeleton, Mechanotransduction +20

Factor VIIIa-mimetic cofactor activity of a bispecific antibody to factors IX/IXa and X/Xa, emicizumab, depends on its ability to bridge the antigens

Takehisa Kitazawa, Keiko Esaki, Tatsuhiko Tachibana et al. · Thrombosis and Haemostasis · 2017 · 193 citations · Full text