Yasushi Ito

Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov et al. · Cell Reports · 2015 · 522 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Jiefei Geng, Yasushi Ito, Linyu Shi et al. · Nature Communications · 2017 · 327 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

High Levels of Human Apolipoprotein A-I in Transgenic Mice Result in Increased Plasma Levels of Small High Density Lipoprotein (HDL) Particles Comparable to Human HDL3

A Walsh, Yasushi Ito, Jan L. Breslow · Journal of Biological Chemistry · 1989 · 243 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A-I. Presentation of a new animal model and mechanistic studies in human Apo A-I transgenic and control mice.

Tony Hayek, Yasushi Ito, Neal Azrolan et al. · Journal of Clinical Investigation · 1993 · 147 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +16

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Palak Amin, Marcus A. Florez, Ayaz Najafov et al. · Proceedings of the National Academy of Sciences · 2018 · 144 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17