One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

Hui Yang, Haoyi Wang, Chikdu Shivalila, +3

Cell

Knockout MouseEngineeringGenome SurgeryGeneticsCrispr/cas-mediated Genome Engineering +11

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

Tianpeng Gu, Fan Guo, Hui Yang, +14

Nature

ChromatinChromatin RemodelingNatural SciencesGeneticsMolecular Epigenetics +11

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Thorold W. Theunissen, Benjamin E. Powell, Haoyi Wang, +18

Cell stem cell

FertilityAdult Stem CellKinase InhibitorsEpigeneticsNaive Human Pluripotency +14

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

Albert W. Cheng, Haoyi Wang, Hui Yang, +7

Cell Research

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Haibo Zhou, Jinlin Su, Xinde Hu, +19

Cell

Neurodegenerative DiseasesNeuroregenerationMedicineGene EditingNeurology +10

Homology-mediated end joining-based targeted integration using CRISPR/Cas9

Xuan Yao, Xing Wang, Xinde Hu, +18

Cell Research

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Jiefei Geng, Yasushi Ito, Linyu Shi, +11

Nature Communications

ApoptosisImmunologyCell DeathDependent ApoptosisCell Death Mechanisms +15

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Haibo Zhou, Junlai Liu, Changyang Zhou, +19

Nature Neuroscience

Transcriptional RegulationSystems BiologyIn Vivo Gene TherapyMultiple GenesCrispr–dcas9-activator Transgenic Mice +10

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Erwei Zuo, Yijun Cai, Kui Li, +26

Cell Research

EngineeringGeneticsOne-step GenerationMolecular GeneticsMonkey Embryos +15

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells

Hui Yang, Linyu Shi, Bang-An Wang, +10

Cell

OocyteEmbryonic Stem CellInduced Pluripotent Stem CellDevelopmental BiologyMedicine +6