Xinde Hu

Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou, Yidi Sun, Rui Yan et al. · Nature · 2019 · 477 citations

Off-target Rna Mutation, Genetics, Molecular Biology +7

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

Haibo Zhou, Jinlin Su, Xinde Hu et al. · Cell · 2020 · 449 citations · Full text

Neurodegenerative Diseases, Neuroregeneration, Medicine +12

Homology-mediated end joining-based targeted integration using CRISPR/Cas9

Xuan Yao, Xing Wang, Xinde Hu et al. · Cell Research · 2017 · 342 citations · Full text

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Haibo Zhou, Junlai Liu, Changyang Zhou et al. · Nature Neuroscience · 2018 · 274 citations

Transcriptional Regulation, Systems Biology, In Vivo Gene Therapy +12

One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs

Erwei Zuo, Yijun Cai, Kui Li et al. · Cell Research · 2017 · 211 citations · Full text

Engineering, Genetics, One-step Generation +17