Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis

Changyang Zhou, Yidi Sun, Rui Yan, +11

Nature

Off-target Rna MutationGeneticsMolecular BiologyGenetic EngineeringGene Editing +5

Breast cancer histopathological image classification using a hybrid deep neural network

Rui Yan, Fei Ren, Zihao Wang, +6

Methods

Convolutional Neural NetworkImage AnalysisMachine LearningMedical ImagingEngineering +10

Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing

Rui Yan, Chan Gu, Di You, +8

Cell stem cell

GeneticsMultiomicsGenomicsEpigeneticsSingle Cell Sequencing +14

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development

Rui Yan, Xin Cheng, Chan Gu, +8

Nature Genetics

ChromatinDevelopmental BiologyGermline DevelopmentEpigenetic ChangeGenetics +11

Richer fusion network for breast cancer classification based on multimodal data

Rui Yan, Fa Zhang, Xiaosong Rao, +8

BMC Medical Informatics and Decision Making

A closed-form estimate of 3D ICP covariance

Sai Manoj Prakhya, Bingbing Liu, Rui Yan, +1

Parameter EstimationEngineeringField RoboticsPoint Cloud ProcessingPoint Cloud +19

Stereoselectivity in <i>N</i>-Iminium Ion Cyclization: Development of an Efficient Synthesis of (±)-Cephalotaxine

Hao Liu, Jing Yu, Xinyu Li, +3

Organic Letters

Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning

Rui Yan, Yijun Shen, Xueyuan Zhang, +6

Medical Image Analysis

UrologyEngineeringMachine LearningDeep LearningTumor Heterogeneity +7

TransSurv: Transformer-Based Survival Analysis Model Integrating Histopathological Images and Genomic Data for Colorectal Cancer

Zhilong Lv, Yuexiao Lin, Rui Yan, +2

IEEE/ACM Transactions on Computational Biology and Bioinformatics

EngineeringDigital PathologyPathologyMulti-image FusionImage Analysis +17

A Hybrid Convolutional and Recurrent Deep Neural Network for Breast Cancer Pathological Image Classification

Rui Yan, Fei Ren, Zihao Wang, +6

Convolutional Neural NetworkEngineeringMachine LearningDigital PathologyPathology +18