RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Yasushi Ito, Dimitry Ofengeim, Ayaz Najafov, +18

Science

ImmunologyCell DeathNeuroinflammationInflammationAutophagy +15

Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim, Yasushi Ito, Ayaz Najafov, +16

Cell Reports

SNARE Proteins Are Required for Macroautophagy

Usha Nair, Anjali Jotwani, Jiefei Geng, +13

Cell

Protein FunctionAutophagySnare ProteinsIntracellular TraffickingCellular Biochemistry +4

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Jiefei Geng, Yasushi Ito, Linyu Shi, +11

Nature Communications

ApoptosisImmunologyCell DeathDependent ApoptosisCell Death Mechanisms +15

Atg22 Recycles Amino Acids to Link the Degradative and Recycling Functions of Autophagy

Zhifen Yang, Ju Huang, Jiefei Geng, +2

Molecular Biology of the Cell

MitophagyMolecular BiologyCytoskeletonRecycling FunctionsCellular Physiology +19

A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

Tomotake Kanki, Ke Wang, Misuzu Baba, +8

Molecular Biology of the Cell

MitophagyGeneticsMolecular GeneticsGenomicsYeast Mutants Defective +14

The Atg1 Kinase Complex Is Involved in the Regulation of Protein Recruitment to Initiate Sequestering Vesicle Formation for Nonspecific Autophagy in<i>Saccharomyces cerevisiae</i>

Heesun Cheong, Usha Nair, Jiefei Geng, +1

Molecular Biology of the Cell

Post-Golgi Sec Proteins Are Required for Autophagy in <i>Saccharomyces cerevisiae</i>

Jiefei Geng, Usha Nair, Kyoko Yasumura-Yorimitsu, +1

Molecular Biology of the Cell

MitophagyProtein SecretionMolecular BiologyMembrane FlowAutophagosome Biogenesis +16

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Palak Amin, Marcus A. Florez, Ayaz Najafov, +9

Proceedings of the National Academy of Sciences

Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy

Jiefei Geng, Misuzu Baba, Usha Nair, +1

The Journal of Cell Biology