Jan L. Breslow

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Andrew Plump, Jonathan D. Smith, Tony Hayek et al. · Cell · 1992 · 2.2K citations

Metabolic Syndrome, Lipid Disorder, Oxysterol +12

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

Yutaka Nakashima, Andrew Plump, Elaine W. Raines et al. · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1994 · 1.7K citations

Vascular Disease, Apoe-deficient Mice, Pathology +20

Moderate Alcohol Intake, Increased Levels of High-Density Lipoprotein and Its Subfractions, and Decreased Risk of Myocardial Infarction

J. Michael Gaziano, Julie E. Buring, Jan L. Breslow et al. · New England Journal of Medicine · 1993 · 1K citations · Full text

Upregulation of VCAM-1 and ICAM-1 at Atherosclerosis-Prone Sites on the Endothelium in the ApoE-Deficient Mouse

Yutaka Nakashima, Elaine W. Raines, Andrew Plump et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 904 citations

Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Jason K. Kim, Jonathan J. Fillmore, Yan Chen et al. · Proceedings of the National Academy of Sciences · 2001 · 771 citations · Full text

Lipoprotein Lipase, Insulin Signaling, Obesity +17