Dan M. Berger

4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors

Allan Wissner, Dan M. Berger, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 2000 · 208 citations · Full text

Pharmaceutical Science, Organic Chemistry, Pharmacotherapy +19

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Lori M. Miller, Scott C. Mayer, Dan M. Berger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations

Medicine, Pathology, Lead Identification +10

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors

Dan M. Berger, Nancy Torres, Minu Dutia et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 35 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4

Dramatic Effect of Solvent Hydrogen Bond Basicity on the Regiochemistry of S_NAr Reactions of Electron-Deficient Polyfluoroarenes

Xiaolun Wang, Edward J. Salaski, Dan M. Berger et al. · Organic Letters · 2009 · 31 citations

Halogenation, Biochemistry, Natural Sciences +10

Novel pyrazolopyrimidines as highly potent B-Raf inhibitors

Martin J. Di Grandi, Dan M. Berger, Darrin W. Hopper et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 29 citations · Full text

Medicinal Chemistry, Medicine, Novel Pyrazolopyrimidines +7