Allan Wissner

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

Eunice L. Kwak, Raffaella Sordella, Daphne W. Bell et al. · Proceedings of the National Academy of Sciences · 2005 · 951 citations · Full text

Antitumor Activity of HKI-272, an Orally Active, Irreversible Inhibitor of the HER-2 Tyrosine Kinase

Sridhar K. Rabindran, Carolyn Discafani, Edward Rosfjord et al. · Cancer Research · 2004 · 628 citations · Full text

Combinatorial chemoprevention of intestinal neoplasia

C Torrance, Peta E. Jackson, Elizabeth A. Montgomery et al. · Nature Medicine · 2000 · 494 citations

Medicine, Gastroenterology, Colorectal Cancer +4

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent

Jonathan D. Bloom, Minu Dutia, Bernard D. Johnson et al. · Journal of Medicinal Chemistry · 1992 · 295 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Experimental Pharmacology +18

Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity

Hwei‐Ru Tsou, Elsebe G. Overbeek-Klumpers, William Hallett et al. · Journal of Medicinal Chemistry · 2005 · 294 citations · Full text

Medicinal Chemistry, Biochemistry, Safer Cyclization Step +13