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Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent
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Altmetric Attention ScorePharmacotherapyExperimental PharmacologyPharmaceutical ChemistryCl 316,243Molecular PharmacologyMedicinal ChemistryPharmacological Study.Beta.3 ReceptorsPotent .Beta.-adrenergic AgonistBiochemistryMechanism Of ActionPharmacological AgentPharmacologyFunctional SelectivityNatural SciencesDiabetesPhysiologyMedicineDrug DiscoveryAlpha-adrenergic Pharmacology
ADVERTISEMENT RETURN TO ISSUEPREVArticleDisodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agentJonathan D. Bloom, Minu D. Dutia, Bernard D. Johnson, Allan Wissner, Michael G. Burns, Elwood E. Largis, Jo Alene Dolan, and Thomas H. ClausCite this: J. Med. Chem. 1992, 35, 16, 3081–3084Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/jm00094a025https://doi.org/10.1021/jm00094a025research-articleACS PublicationsRequest reuse permissionsArticle Views1576Altmetric-Citations238LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts