Elwood Largis

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent

Jonathan D. Bloom, Minu Dutia, Bernard D. Johnson et al. · Journal of Medicinal Chemistry · 1992 · 295 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Experimental Pharmacology +18

Hypercholesterolemia in the Rabbit Induced by Feeding Graded Amounts of Low-Level Cholesterol

Frank D. Kolodgie, Andrew S. Katocs, Elwood Largis et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1996 · 144 citations · Full text

Nutrition, Graded Amounts, Hyperlipidemia +20

CL 277,082: a novel inhibitor of ACAT-catalyzed cholesterol esterification and cholesterol absorption.

Elwood Largis, Chao-Hsiung Wang, Vern G. DeVries et al. · Journal of Lipid Research · 1989 · 127 citations · Full text

Beta-3 adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines.

Jo Alene Dolan, Helen A. Muenkel, Michael Burns et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 81 citations

Novel (4-Piperidin-1-yl)-phenyl Sulfonamides as Potent and Selective Human β3 Agonists

Baihua Hu, John W. Ellingboe, Stella Han et al. · Bioorganic & Medicinal Chemistry · 2001 · 45 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +10