Thomas H. Claus

Disodium (R,R)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316,243). A potent .beta.-adrenergic agonist virtually specific for .beta.3 receptors. A promising antidiabetic and antiobesity agent

Jonathan D. Bloom, Minu Dutia, Bernard D. Johnson et al. · Journal of Medicinal Chemistry · 1992 · 295 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Experimental Pharmacology +18

Small-Molecule Ghrelin Receptor Antagonists Improve Glucose Tolerance, Suppress Appetite, and Promote Weight Loss

William P. Esler, Joachim Rudolph, Thomas H. Claus et al. · Endocrinology · 2007 · 227 citations · Full text

Nutrition, Food Intake, Glucose Tolerance +18

Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a β3-adrenoceptor agonist

Masoud Ghorbani, Thomas H. Claus, Jean Himms‐Hagen · Biochemical Pharmacology · 1997 · 195 citations

Obesity, Metabolic Syndrome, Diet-induced Obesity +13

Quinazolinone Derivatives as Orally Available Ghrelin Receptor Antagonists for the Treatment of Diabetes and Obesity

Joachim Rudolph, William P. Esler, Stephen O’Connor et al. · Journal of Medicinal Chemistry · 2007 · 157 citations · Full text

Food Intake, Pharmacotherapy, Type 1A +17

A Potent and Highly Selective VPAC2 Agonist Enhances Glucose-Induced Insulin Release and Glucose Disposal

Manami Tsutsumi, Thomas H. Claus, Yin Liang et al. · Diabetes · 2002 · 124 citations · Full text

Insulin Signaling, Gastrointestinal Peptide Hormone, Molecular Pharmacology +18