Edward J. Salaski

Pyranonaphthoquinone Lactones: A New Class of AKT Selective Kinase Inhibitors Alkylate a Regulatory Loop Cysteine

Edward J. Salaski, Girija Krishnamurthy, Weidong Ding et al. · Journal of Medicinal Chemistry · 2009 · 72 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Drug Resistance +16

Efficient total synthesis of (.+-.)-anatoxin a

Rick Danheiser, J. M. JUN. MORIN, Edward J. Salaski · Journal of the American Chemical Society · 1985 · 69 citations

Altmetrics, Biosynthesis, Engineering +12

Aristolochene biosynthesis and enzymatic cyclization of farnesyl pyrophosphate

David E. Cane, Panchami Prabhakaran, Edward J. Salaski et al. · Journal of the American Chemical Society · 1989 · 66 citations

Molecular Sciences, Biosynthesis, Engineering +13

Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines

Lourdes Toral‐Barza, Weiguo Zhang, Xinyi Huang et al. · Molecular Cancer Therapeutics · 2007 · 58 citations · Full text

Chemoprevention Strategy, Allosteric Inhibitors, Mechanistic Involvement +18

Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates

Jeremy I. Levin, J.M. Chen, Katherine Cheung et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 49 citations · Full text

Acyclic Sulfonamide Hydroxamates, Medicinal Chemistry, Pharmaceutical Science +11