Charles A. Omer

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky et al. · Nature Structural & Molecular Biology · 2004 · 612 citations

Signal Transduction, Signaling Pathway, Cell Regulation +8

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 538 citations

Farnesyltransferase Induces Regression, Tumor Biology, Chemoprevention Strategy +12

A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis

Rebecca E. Barrington, Mark A. Subler, Elaine Rands et al. · Molecular and Cellular Biology · 1998 · 172 citations · Full text

Ras/myc Tumors, Farnesyltransferase Inhibitor L-744,832, Chemoprevention Strategy +14

Characterization of recombinant human farnesyl-protein transferase: Cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases

Charles A. Omer, Astrid M. Kral, Ronald E. Diehl et al. · Biochemistry · 1993 · 137 citations

Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus

Charles A. Omer, Reijer Lenstra, Patricia J. Litle et al. · Journal of Bacteriology · 1990 · 113 citations · Full text

Biosynthesis, Herbicide-inducible Cytochromes P-450, Cellular Enzymology +12