Concepedia

Author

A.G. Pavlovsky

Pfizer (United States)

Also Known As

A Pavlovsky, A. G. PAVLOVSKY, A. G. Pavlovsky, A. PAVLOVSKY, A. Pavlovsky, A.G. Pavlovsky, Alexander G. Pavlovsky, Alexander Pavlovsky, H. Chen

78

Publications

2.8K

Citations

29

H-Index

50

Concepts

All Affiliations

Pfizer (United States)University of ToledoA.V. Shubnikov Institute of CrystallographyCancer Research CenterBirkbeck, University of London
AP

About

A.G. Pavlovsky is an author at Pfizer (United States) specializing in biochemistry, medicine, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Biochemistry

19

25

1.1K

2

Medicine

17

23

1.5K

3

Natural Sciences

17

23

1K

4

Engineering

2

2

66

5

Biomolecular Engineering

1

1

59

A.G. Pavlovsky

×

40

Publications

2.6K

Citations

28

H-Index

YearCitations

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Jeffrey F. Ohren, Huifen Chen, A.G. Pavlovsky,

Nature Structural & Molecular Biology

2004

612

Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects

Adam R. Johnson, A.G. Pavlovsky, Daniel F. Ortwine,

Journal of Biological Chemistry

2007

209

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

Yunmei Wang, Huiyun Gao, Can Shi,

Nature Communications

2017

155

Crystal structure of human recombinant interleukin‐4 at 2.25 Å resolution

Alexander Wlodaver, A.G. Pavlovsky, Alla Gustchina

FEBS Letters

1992

119

X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily

V. Dhanaraj, Q-Z Ye, LL Johnson,

Structure

1996

115

Structure−Activity Relationships and Pharmacokinetic Analysis for a Series of Potent, Systemically Available Biphenylsulfonamide Matrix Metalloproteinase Inhibitors

Patrick O’Brien, Daniel F. Ortwine, A.G. Pavlovsky,

Journal of Medicinal Chemistry

2000

97

A Rationalization of the Acidic pH Dependence for Stromelysin-1 (Matrix Metalloproteinase-3) Catalysis and Inhibition

Linda L. Johnson, A.G. Pavlovsky, Adam R. Johnson,

Journal of Biological Chemistry

2000

75

X‐ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: Implications for inhibitor selectivity

A.G. Pavlovsky, Mark Williams, Qi‐Zhuang Ye,

Protein Science

1999

72

2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles—O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)

Joseph S. Warmus, Cathlin Flamme, Lu Yan Zhang,

Bioorganic & Medicinal Chemistry Letters

2008

67

Thermodynamic and Structure Guided Design of Statin Based Inhibitors of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase

Ronald W. Sarver, Elizabeth Bills, Gary L. Bolton,

Journal of Medicinal Chemistry

2008

64

Page 1