Adam R. Johnson

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 810 citations

Medicine, Molecular Biology, Oncology +7

Resolving <i>TYK2</i> locus genotype-to-phenotype differences in autoimmunity

Calliope A. Dendrou, Adrián Cortés, Lydia Shipman et al. · Science Translational Medicine · 2016 · 260 citations

Life Sciences, Genetics, Molecular Genetics +17

Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton’s Tyrosine Kinase Inhibitor in Early Clinical Development

James J. Crawford, Adam R. Johnson, Dinah Misner et al. · Journal of Medicinal Chemistry · 2018 · 247 citations · Full text

Medicine, Immunology, Pharmacology +17

Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects

Adam R. Johnson, A.G. Pavlovsky, Daniel F. Ortwine et al. · Journal of Biological Chemistry · 2007 · 211 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases

Snahel Patel, Joshua D. Webster, Eugene Varfolomeev et al. · Cell Death and Differentiation · 2019 · 146 citations · Full text

Medicine, Cancer Biology, Oncology +9