Snahel Patel

Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease

Claire E. Le Pichon, William J. Meilandt, Sara L. Domínguez et al. · Science Translational Medicine · 2017 · 158 citations

RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases

Snahel Patel, Joshua D. Webster, Eugene Varfolomeev et al. · Cell Death and Differentiation · 2019 · 139 citations · Full text

Immunology, Pathology, Cell Death +16

Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models

Snahel Patel, Frederick Cohen, Brian J. Dean et al. · Journal of Medicinal Chemistry · 2014 · 86 citations · Full text

Cell Death, Neurodegeneration Models, Signaling Pathway +20

Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer’s Disease

Snahel Patel, William J. Meilandt, Rebecca I. Erickson et al. · Journal of Medicinal Chemistry · 2017 · 71 citations · Full text

Selective Inhibitors, Alzheimer ’, Superior Kinase Selectivity +19

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

Francis Grafton, Jaclyn J. Ho, Sara Ranjbarvaziri et al. · eLife · 2021 · 61 citations · Full text

Cardiac Muscle, Convolutional Neural Network, Engineering +21