Concepedia

Frederick Cohen

FC

Statistics

Publications

31

Citations

2K

H-Index

25

Active since

1974

Affiliations

University of California, Irvine(Current)

University of California, San Francisco

University of South Florida

Gene Therapy Laboratory

Eos Neuroscience (United States)

Frederick Cohen is an author at University of California, Irvine specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

1974–2024

31

Publications

31

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 346 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

John A. Flygare, Maureen H. Beresini, Nageshwar Budha et al. · Journal of Medicinal Chemistry · 2012 · 248 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies

Daniel Robbins, Mark Noviski, Ying Siow Tan et al. · Journal of Medicinal Chemistry · 2024 · 96 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Discovery of Dual Leucine Zipper Kinase (DLK, MAP3K12) Inhibitors with Activity in Neurodegeneration Models

Snahel Patel, Frederick Cohen, Brian J. Dean et al. · Journal of Medicinal Chemistry · 2014 · 91 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques

Paola Di Lello, Richard Pastor, Jeremy Murray et al. · Journal of Medicinal Chemistry · 2017 · 89 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +17

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