Maureen H. Beresini

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 332 citations · Full text

Molecular Docking, Ubiquitin Binding, Drug Target +7

ANGPTL3 Stimulates Endothelial Cell Adhesion and Migration via Integrin αvβ3 and Induces Blood Vessel Formation in Vivo

Gieri Camenisch, M. Teresa Pisabarro, Daniel Sherman et al. · Journal of Biological Chemistry · 2002 · 249 citations · Full text

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

John A. Flygare, Maureen H. Beresini, Nageshwar Budha et al. · Journal of Medicinal Chemistry · 2012 · 247 citations · Full text

Apoptosis, Cell Death, Clinical Candidate +20

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Hoangdung Ho, Anh Miu, Mary Kate Alexander et al. · Nature · 2018 · 173 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9

Generation of an LFA-1 Antagonist by the Transfer of the ICAM-1 Immunoregulatory Epitope to a Small Molecule

Thomas R. Gadek, Daniel J. Burdick, Robert S. McDowell et al. · Science · 2002 · 169 citations

Immunology, Immune Regulation, Immunodominance +18