Paola Di Lello

USP7 small-molecule inhibitors interfere with ubiquitin binding

Lorna Kategaya, Paola Di Lello, Lionel Rougé et al. · Nature · 2017 · 332 citations · Full text

Molecular Docking, Ubiquitin Binding, Drug Target +7

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Bradford Graves, Thelma Thompson, Mingxuan Xia et al. · Proceedings of the National Academy of Sciences · 2012 · 223 citations · Full text

Dimeric Protein Complexes, Molecular Biology, Mdmx Dimerization +16

Structure of the Tfb1/p53 Complex: Insights into the Interaction between the p62/Tfb1 Subunit of TFIIH and the Activation Domain of p53

Paola Di Lello, Lisa M. Jenkins, Tamara Jones et al. · Molecular Cell · 2006 · 200 citations · Full text

Activation Domain, P62/tfb1 Subunit, Molecular Biology +7

An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

Thijs J. Hagenbeek, Marc Hafner, Rana Mroue et al. · Nature Cancer · 2023 · 169 citations · Full text

Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

Yingnan Zhang, Charles Eigenbrot, Lijuan Zhou et al. · Journal of Biological Chemistry · 2013 · 151 citations · Full text

Signal Transduction, Biochemistry, Peptide Library +6