Francis Grafton

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

Francis Grafton, Jaclyn J. Ho, Sara Ranjbarvaziri et al. · eLife · 2021 · 64 citations · Full text

Pharmacy, Pharmacology, Toxicology +15

Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy

Jin Yang, Francis Grafton, Sara Ranjbarvaziri et al. · Science Translational Medicine · 2022 · 53 citations

Medicine, Cardiology, Pharmacology +11

Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice

Sara Ranjbarvaziri, Aliya Zeng, Iris Wu et al. · Nature Communications · 2024 · 50 citations · Full text

Life Sciences, Cardiology, Molecular Biology +16

Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection

Francesca S. Gazzaniga, Diogo M. Camacho, Meng Wu et al. · Frontiers in Cellular and Infection Microbiology · 2021 · 43 citations · Full text

Life Sciences, Immunology, Microbiology +17

Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method

Mahnaz Maddah, Mohammad A. Mandegar, Keri Dame et al. · Journal of Pharmacological and Toxicological Methods · 2020 · 41 citations · Full text

Medicine, Cell Biology, Toxicology +17