Francis Grafton

Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

Francis Grafton, Jaclyn J. Ho, Sara Ranjbarvaziri et al. · eLife · 2021 · 61 citations · Full text

Cardiac Muscle, Convolutional Neural Network, Engineering +21

Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy

Jin Yang, Francis Grafton, Sara Ranjbarvaziri et al. · Science Translational Medicine · 2022 · 44 citations

Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection

Francesca S. Gazzaniga, Diogo M. Camacho, Meng Wu et al. · Frontiers in Cellular and Infection Microbiology · 2021 · 39 citations · Full text

Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice

Sara Ranjbarvaziri, Aliya Zeng, Iris Wu et al. · Nature Communications · 2024 · 39 citations · Full text

Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method

Mahnaz Maddah, Mohammad A. Mandegar, Keri Dame et al. · Journal of Pharmacological and Toxicological Methods · 2020 · 38 citations · Full text