Brian Aquila

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Adriana E. Tron, Matthew A. Belmonte, Ammar Adam et al. · Nature Communications · 2018 · 479 citations · Full text

Photoredox Mediated Nickel Catalyzed Cross-Coupling of Thiols With Aryl and Heteroaryl Iodides via Thiyl Radicals

Martins S. Oderinde, Mathieu Frenette, Daniel Robbins et al. · Journal of the American Chemical Society · 2016 · 441 citations

Highly Chemoselective Iridium Photoredox and Nickel Catalysis for the Cross‐Coupling of Primary Aryl Amines with Aryl Halides

Martins S. Oderinde, Natalie H. Jones, Antoine Juneau et al. · Angewandte Chemie International Edition · 2016 · 208 citations

Diverse Aryl Iodides, Chemical Engineering, Cross-coupling Reaction +13

Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain

Gizem Akçay, Matthew A. Belmonte, Brian Aquila et al. · Nature Chemical Biology · 2016 · 191 citations · Full text

Protein Chemistry, Medicinal Chemistry, Biochemistry +8

A study of the reactivity of S^(VI)–F containing warheads with nucleophilic amino-acid side chains under physiological conditions

H. G. MUKHERJEE, J.E. Debreczeni, J. Breed et al. · Organic & Biomolecular Chemistry · 2017 · 156 citations