Teng Teng

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman et al. · Nature Medicine · 2018 · 491 citations · Full text

Tumor Biology, Medicine, Rna Splicing +9

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

Michael Seiler, Shouyong Peng, Anant A. Agrawal et al. · Cell Reports · 2018 · 458 citations · Full text

Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint

Stefano Fumagalli, Vasily V. Ivanenkov, Teng Teng et al. · Genes & Development · 2012 · 221 citations · Full text

Novel G2/m Checkpoint, Ribosome Biogenesis, Cell Regulation +12

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Teng Teng, Jennifer Tsai, Xiaoling Puyang et al. · Nature Communications · 2017 · 147 citations · Full text

Circulating Tumor Cells Exhibit Metastatic Tropism and Reveal Brain Metastasis Drivers

Rémi Klotz, Amal Thomas, Teng Teng et al. · Cancer Discovery · 2019 · 136 citations · Full text