Sequence analysis of mutations and translocations across breast cancer subtypes

Shantanu Banerji, Kristian Cibulskis, Claudia Rangel‐Escareño, +44

Nature

Recurrent MutationsBreast OncologyOncologyEngineeringSomatic Variant +12

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

Austin Dulak, Petar Stojanov, Shouyong Peng, +36

Nature Genetics

Somatic VariantEsophageal CancerTumor HeterogeneityMedicineGenetics +7

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman, +33

Nature Medicine

Tumor BiologyMedicineRna SplicingInduces LethalityCell Biology +7

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

Michael Seiler, Shouyong Peng, Anant A. Agrawal, +4

Cell Reports

Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

Rachel Darman, Michael Seiler, Anant A. Agrawal, +33

Cell Reports

GeneticsRna SplicingMolecular BiologyMolecular GeneticsCancer Biology +15

Paired exome analysis of Barrett's esophagus and adenocarcinoma

Matthew D. Stachler, Amaro Taylor‐Weiner, Shouyong Peng, +20

Nature Genetics

OncologyEsophagusEsophageal CancerMedicineGastroenterology +5

A Sequence Motif within Chromatin Entry Sites Directs MSL Establishment on the Drosophila X Chromosome

Artyom A. Alekseyenko, Shouyong Peng, Erica Larschan, +8

Cell

ChromatinSequence MotifDevelopmental BiologyChromatin StructureChromatin Remodeling +9

MSL Complex Is Attracted to Genes Marked by H3K36 Trimethylation Using a Sequence-Independent Mechanism

Erica Larschan, Artyom A. Alekseyenko, Andrey A. Gortchakov, +6

Molecular Cell

H3k36 TrimethylationMolecular ResearchNatural SciencesGeneticsMolecular Biology +5

SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas

Hideo Watanabe, Qiuping Ma, Shouyong Peng, +17

Journal of Clinical Investigation

PathologyCancer BiologyTumor BiologyTranscriptional RegulationTumor Heterogeneity +15

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Teng Teng, Jennifer Tsai, Xiaoling Puyang, +27

Nature Communications